Genotyping arrays enable the direct measurement of an individuals genotype at thousands of markers. 'plinkQC' facilitates genotype quality control for genetic association studies as described by Anderson and colleagues (2010) <doi:10.1038/nprot.2010.116>. It makes 'PLINK' basic statistics (e.g. missing genotyping rates per individual, allele frequencies per genetic marker) and relationship functions accessible from 'R' and generates a per-individual and per-marker quality control report. Individuals and markers that fail the quality control can subsequently be removed to generate a new, clean dataset. Removal of individuals based on relationship status is optimised to retain as many individuals as possible in the study.
| Version: | 0.3.4 | 
| Depends: | R (≥ 3.6.0) | 
| Imports: | methods, optparse, data.table (≥ 1.11.0), R.utils, ggplot2, ggforce, ggrepel, cowplot, UpSetR, dplyr, igraph (≥ 1.2.4), sys | 
| Suggests: | testthat, mockery, formatR, knitr, rmarkdown | 
| Published: | 2021-07-15 | 
| DOI: | 10.32614/CRAN.package.plinkQC | 
| Author: | Hannah Meyer | 
| Maintainer: | Hannah Meyer <hannah.v.meyer at gmail.com> | 
| BugReports: | https://github.com/meyer-lab-cshl/plinkQC/issues | 
| License: | MIT + file LICENSE | 
| URL: | https://meyer-lab-cshl.github.io/plinkQC/ | 
| NeedsCompilation: | no | 
| SystemRequirements: | plink (1.9) | 
| Materials: | README, NEWS | 
| CRAN checks: | plinkQC results | 
| Reference manual: | plinkQC.html , plinkQC.pdf | 
| Vignettes: | AncestryCheck (source, R code) 1000Genomes (source, R code) HapMap (source, R code) GenotypeQC_with_plinkQC (source, R code) | 
| Package source: | plinkQC_0.3.4.tar.gz | 
| Windows binaries: | r-devel: plinkQC_0.3.4.zip, r-release: plinkQC_0.3.4.zip, r-oldrel: plinkQC_0.3.4.zip | 
| macOS binaries: | r-release (arm64): plinkQC_0.3.4.tgz, r-oldrel (arm64): plinkQC_0.3.4.tgz, r-release (x86_64): plinkQC_0.3.4.tgz, r-oldrel (x86_64): plinkQC_0.3.4.tgz | 
| Old sources: | plinkQC archive | 
Please use the canonical form https://CRAN.R-project.org/package=plinkQC to link to this page.