PCRedux: Quantitative Polymerase Chain Reaction (qPCR) Data Mining and Machine Learning Toolkit as Described in Burdukiewicz (2022) <doi:10.21105/Joss.04407>

Extracts features from amplification curve data of quantitative Polymerase Chain Reactions (qPCR) according to Pabinger et al. 2014 <doi:10.1016/j.bdq.2014.08.002> for machine learning purposes. Helper functions prepare the amplification curve data for processing as functional data (e.g., Hausdorff distance) or enable the plotting of amplification curve classes (negative, ambiguous, positive). The hookreg() and hookregNL() functions of Burdukiewicz et al. (2018) <doi:10.1016/j.bdq.2018.08.001> can be used to predict amplification curves with an hook effect-like curvature. The pcrfit_single() function can be used to extract features from an amplification curve.

Version: 1.2-0
Depends: R (≥ 3.5.0)
Imports: changepoint, chipPCR, ecp, fda.usc, MBmca, pbapply, pracma, qpcR, robustbase, segmented, shiny, stats, utils, zoo
Suggests: DT, future, knitr, listenv, RDML, readxl, rmarkdown, shinycssloaders, spelling, testthat, xtable
Published: 2025-06-13
DOI: 10.32614/CRAN.package.PCRedux
Author: Stefan Roediger ORCID iD [aut], Michal Burdukiewicz ORCID iD [aut], Andrej-Nikolai Spiess ORCID iD [cre, aut], Konstantin A. Blagodatskikh ORCID iD [aut], Dominik Rafacz ORCID iD [ctb]
Maintainer: Andrej-Nikolai Spiess <draspiess at gmail.com>
BugReports: https://github.com/PCRuniversum/PCRedux/issues
License: MIT + file LICENSE
URL: https://CRAN.R-project.org/package=PCRedux
NeedsCompilation: no
Language: en-US
Materials: README NEWS ChangeLog
CRAN checks: PCRedux results

Documentation:

Reference manual: PCRedux.pdf
Vignettes: PCRedux package - an overview (source)

Downloads:

Package source: PCRedux_1.2-0.tar.gz
Windows binaries: r-devel: not available, r-release: PCRedux_1.2-0.zip, r-oldrel: PCRedux_1.2-0.zip
macOS binaries: r-release (arm64): PCRedux_1.2-0.tgz, r-oldrel (arm64): PCRedux_1.2-0.tgz, r-release (x86_64): not available, r-oldrel (x86_64): not available
Old sources: PCRedux archive

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