BuyseTest: Generalized Pairwise Comparisons
Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.
| Version: | 3.3.4 |
| Depends: | R (≥ 3.5.0), Rcpp |
| Imports: | data.table, doSNOW, foreach, ggplot2, methods, lava, parallel, prodlim, riskRegression, rlang, scales, stats, stats4, utils |
| LinkingTo: | Rcpp, RcppArmadillo |
| Suggests: | cvAUC, mvtnorm, pbapply, pROC, R.rsp, survival, testthat |
| Published: | 2025-09-24 |
| DOI: | 10.32614/CRAN.package.BuyseTest |
| Author: | Brice Ozenne 
[aut, cre],
Eva Cantagallo [aut],
William Anderson [aut],
Julien Peron [ctb],
Johan Verbeeck [ctb] |
| Maintainer: | Brice Ozenne <brice.mh.ozenne at gmail.com> |
| BugReports: | https://github.com/bozenne/BuyseTest/issues |
| License: | GPL-3 |
| URL: | https://github.com/bozenne/BuyseTest |
| NeedsCompilation: | yes |
| Citation: | BuyseTest citation info |
| Materials: | NEWS |
| In views: | CausalInference |
| CRAN checks: | BuyseTest results |
Documentation:
| Reference manual: | BuyseTest.html , BuyseTest.pdf |
| Vignettes: |
BuyseTest: overview (source) BuyseTest: paired (source) BuyseTest: wilcoxon test (source) |
Downloads:
| Package source: | BuyseTest_3.3.4.tar.gz |
| Windows binaries: | r-devel: BuyseTest_3.3.4.zip, r-release: BuyseTest_3.3.4.zip, r-oldrel: BuyseTest_3.3.4.zip |
| macOS binaries: | r-release (arm64): BuyseTest_3.3.4.tgz, r-oldrel (arm64): BuyseTest_3.3.4.tgz, r-release (x86_64): BuyseTest_3.3.4.tgz, r-oldrel (x86_64): BuyseTest_3.3.4.tgz |
| Old sources: | BuyseTest archive |
Linking:
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